THE RESISTANCE OF CANCER CELLS TO PALBOCICLIB, A CYCLIN-DEPENDENT KINASE 4/6 INHIBITOR, IS MEDIATED BY THE ABCB1 TRANSPORTER

The Resistance of Cancer Cells to Palbociclib, a Cyclin-Dependent Kinase 4/6 Inhibitor, is Mediated by the ABCB1 Transporter

Litter Accessories Palbociclib was approved by the United States Food and Drug Administration for use, in combination with letrozole, as a first-line treatment for estrogen receptor-positive/human epidermal growth factor receptor 2-negative (ER+/HER2-) postmenopausal metastatic breast cancer.However, recent studies show that palbociclib may be an i

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Eosinophilic colitis

Introduction: eosinophilic colitis is a gastrointestinal disorder characterized by an inflammatory infiltration in the colon SWEET CORN and rectum, with predominance of eosinophils, its clinical manifestation depends on the affected intestinal epithelium layer, the exclusive affectation of the colon is exceptional, intestinal obstruction is the mos

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Basic, simple and extendable kinetic model of protein synthesis

Protein 7 Piece Outdoor Sectional with Ottoman synthesis is one of the most fundamental biological processes.Despite existence of multiple mathematical models of translation, surprisingly, there is no basic and simple chemical kinetic model of this process, derived directly from the detailed kinetic scheme.One of the reasons for this is that the tr

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